Publications

Mao, Y., Nakel, T., Erbasol Serbes, I., Joshi, S., Tekleyohans, D.G., Baum, T., Gro?-Hardt, R. (2023). ECS1 and ECS2 suppress polyspermy and the formation of haploid plants by promoting double fertilization. eLife.

Mao, Y., Nakel, T., Erbasol Serbes, I., Tekleyohans, D.G., Joshi, S., Baum, T., Gro?-Hardt, R. (2022). ECS1 and ECS2 regulate polyspermy and suppress the formation of haploid plants by promoting double fertilization. bioRxiv.

Heydlauff, J., Erbasol Serbes, I., Vo, D., Mao, Y., Gieseking, S., Nakel, T., Harten, T., V?lz, R., Hoffmann, A., Gro?-Hardt, R. (2022). Dual and opposing roles of EIN3 reveal a generation conflict during seed growth. Molecular plant 15, no. 2: 363-371.

Joshi, S., Hater, F., Eirich, J., Palovaara, J., Ellinghaus, H., Heinkow, P., Callenius, H., Peter, A., Schweser, O., Kubitschke, M., Madduri, M.K., Mathew, A. J., Ciacchi, L. C., Kirstein, J., Maedler, K., Masseck, O. A., Finkemeier, I., Radmacher, M., Gro?-Hardt, R. (2021). A versatile mitochondria isolation-and analysis-pipeline generates 3D nano-topographies and mechano-physical surface maps of single organelles. bioRxiv.

Hater, F., Nakel, T., Gro?-Hardt, R. (2020). Reproductive multitasking: the female gametophyte. Annual review of plant biology 71: 517-546.

Mao, Y., Gabel, A., Nakel, T., Vieh?ver, P., Baum, T., Tekleyohans, D. G., Vo, D., Grosse, I., Gro?-Hardt, R. (2020). Selective egg cell polyspermy bypasses the triploid block. eLife 9: e52976.

Tekleyohans, D. G., Gro?-Hardt, R (2019). New advances and future directions in plant polyspermy. Molecular Reproduction and Development.

Erbasol Serbes, I. , Palovaara, J., Gro?-Hardt, R. (2019). Development and function of the flowering plant female gametophyte. in Current Topics in Developmental Biology, U. Grossniklaus, Ed. (Academic Press, 2019), vol. 131, pp. 401-434.

Nakel, T., Tekleyohans, D.G., Mao, Y., Fuchert, G., Vo, D., Gro?-Hardt, R. (2017). Triparental Plants provide direct evidence for polyspermy induced polyploidy. Nature Communications. 8, 1033.

Tekleyohans, D.G., Mao, Y., K?gi, C., Stierhof, Y-D., Gro?-Hardt, R. (2017). Polyspermy Barriers: A Plant Perspective. Current Opinion in Plant Biology 35:131-137.

Tekleyohans, D.G., Nakel, T., Gro?-Hardt, R. (2016). Patterning the Female Gametophyte of Flowering Plants. Plant Physiology 173(1):122-129.

Mendes, M.A., Guerra, R.F., Castelnovo, B., Silva-Velazquez, Y., Morandini, P., Manrique, S., Baumann, N., Gro?-Hardt, R., Dickinson, H., Colombo, L. (2016). Live and let die: A REM complex promotes fertilization Through synergid cell death in Arabidopsis. Development 143(15):2780-90.

Maruyama D, V?lz R, Takeuchi H, Mori T, Igawa T, Kurihara D, Kawashima T, Ueda M, Itoh M, Masaaki U, Nishikawa S, Gro?-Hardt R, Higashiyama T (2015). Rapid elimination of the persistent synergid through a cell-fusion for polytubey block. Cell 161:907-18.

Wunderlich M, Gro?-Hardt R, Sch?ffl F. Heat shock factor HSFB2a involved in gametophyte development of Arabidopsis thaliana and its expression is controlled by a heatinducible long non-coding antisense RNA (2014). Plant Mol Bio 85:541-50.

Heydlauff J, Gro?-Hardt (2014). Love is a battlefield: programmed cell death during fertilization. J Exp Bot 65, 1323-30.

V?lz, R., Heydlauff, J., Ripper, D., von Lyncker, L., Gro?-Hardt, R. (2013) Ethylene signaling is required for synergid degeneration and the establishment of a pollen tube block. Developmental Cell 25:310-316 reviewed in Dev Cell (2013). 25,222-4.

V?lz, R., von Lyncker, L., Baumann, N., Dresselhaus, T., Sprunck, S., Gro?-Hardt, R. (2012). LACHESIS-dependent egg-cell signaling regulates the development of female gametophytic cells. Development 139:498-502.

Sprunck, S., Gro?-Hardt, R. (2011). Nuclear behavior, cell polarity, and cell specification in the female gametophyte. Sex Plant Reprod. 24:123-136.

Kirioukhova, O., Johnston, A.J., Kleen, D., K?gi, C., Baskar, R., Moore, J.M., B?umlein, H., Gro?-Hardt, R., Grossniklaus, U. (2011). Female gametophytic cell specification and seed development require the function of the putative Arabidopsis INCENP ortholog WYRD. Development 138(16):3409-3420.

K?gi, C., Baumann, N., Nielsen, N., Stierhof, Y.-D., Gro?-Hardt, R. (2010). The gametic central cell of Arabidopsis determines the lifespan of adjacent accessory cells. Proc Natl Acad Sci U S A 107(51):22350-22355 V?lz, R. and  Gro?-Hardt, R. (2010). Female gametophytic mutants: Diagnosis and characterization. In: Plant Developmental Biology. Hennig L and K?hler C (eds). Humana Press Inc. Totowa, USA.

K?gi, C. and Gro?-Hardt, R. (2010). Analyzing female gametophyte development and function: There is more than one way to crack an egg. Eur J Cell Biol. 89(2-3):258-261.

Gro?-Hardt, R. (2008). Entwicklung. Taschenlehrbuch Biologie Botanik, Hrsg.: K Munck, Georg Thieme Verlag KG, Stuttgart.

Gro?-Hardt, R. (2008). Bildung von Keimzellen in Blütenpflanzen in: Wachstum, Eskalation, Steuerung und Grenzen, Hrsg.: C Nüsslein-Volhard u.a., Georg Thieme Verlag KG, Stuttgart.

Moll, C., von Lyncker, L., Zimmermann, S., K?gi, C., Baumann, N., Twell, D., Grossniklaus, U.,  Gro?-Hardt, R. (2008). CLO/GFA1 and ATO are novel regulators of gametic cell fate in plants. Plant Journal 56(6):913-921.

Moll, C., Nielsen, N.,  Gro?-Hardt, R. (2008). Mutants with aberrant numbers of gametic cells shed new light on old questions. Plant Biol. 10(5):529-533.

K?gi, C. and  Gro?-Hardt, R. (2007). How females become complex: cell differentiation in the gametophyte. Curr Opin Plant Biol. 10(6):633-638.

Gro?-Hardt, R., K?gi, C., Baumann, N., Moore, J.M., Baskar, R., Gagliano, W.B., Jürgens, G., Grossniklaus, U. (2007). LACHESIS restricts gametic cell fate in the female gametophyte of Arabidopsis. PLoS Biol 5: e47 (pdf) reviewed in Science Editors' Choice (2007) Vol. 315:1195.

The paper above was featured in:

Zahn L.M. (2007). Cell fate and gametes. Science 315: 1195.

Würschum, T.,  Gro?-Hardt, R., Laux, T. (2006) APETALA2 regulates the stem cell niche in the Arabidopsis shoot meristem. Plant Cell 18(2):295-307.

Haecker, A.,  Gro?-Hardt, R., Geiges, B., Sarkar, A., Herrmann, M., and Laux, T. (2004). Expression dynamics of WOX genes mark cell fate decisions during early embryonic patterning in Arabidopsis thaliana. Development 131: 657-668.

Sieber, P., Gheyselinck, J.,  Gro?-Hardt, R., Laux, T., Grossniklaus, U., and Schneitz, K. (2004). Pattern formation during early ovule development in Arabidopsis thaliana. Dev Biol. 273(2):321-334.

Gro?-Hardt, R. and Laux, T. (2003). Stem cell regulation in the shoot meristem. J. Cell Sci. 116: 1659-1666.

Gro?-Hardt, R., Lenhard, M., and Laux, T. (2002). WUSCHEL signaling functions in interregional communication during Arabidopsis ovule development. Genes & Development 16: 1129-1138.

Gro?-Hardt, R. and Laux, T. (2000). Shoots and buds. Encyclopedia of Life Sciences, Macmillan Publishers Ltd.